Experimental Autoimmune Encephalomyelitis
نویسنده
چکیده
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). MS is also named encephalomyelitis disseminata (ED). EAE has been also called experimental allergic encephalomyelitis, but the word `allergic` is more and more replaced by the word `autoimmune`. This has to do with the deeper understanding of the disease biology that has been gathered over the last years. MS is a chronic autoimmune disease of the central nervous system (CNS) that leads to inflammation, demyelination and axonal loss. The CNS lesions cause neurological deficits.
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